Formaldehyde → HCID 53918420, compound

HRID 1388138Notes

Reaction equation

HRID 1388138 reaction equation
[CH2:1]([O:3][C:4](=[O:22])[CH:5]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)[C:6](O)=O)[CH3:2].C=O.N1CCCCC1>N1C=CC=CC=1>[CH2:1]([O:3][C:4](=[O:22])[C:5](=[CH2:6])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH:16]1[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]1)[CH3:2]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8082PiperidineHCID 54511522HCID 54511522, compound

Product 1

HCID 53918420HCID 53918420, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

9.2 g of 9-cyclohexyl-2-methylenenonanoic acid ethyl ester, in the form of a colourless oil, which is purified by chromatography on silica gel (migrating agent: 95:5 petroleum ether/ethyl acetate), are obtained by the procedure described in Example (1b) from 16.2 g of (7-cyclohexylheptyl)-malonic acid ethyl ester, 1.86 g of paraformaldehyde, 11.5 ml of pyridine and 0.6 ml of piperidine.

Workup

  1. custom9.2 g of 9-cyclohexyl-2-methylenenonanoic acid ethyl ester, in the form of a colourless oil, which is purified by chromatography on silica gel (migrating agent: 95:5 petroleum ether/ethyl acetate)
  2. customare obtained by the procedure

Sources & evidence

ORD record
ord-e96154c6faae48f2b136725cd360058c
Source dataset
uspto-grants-1984_02
Patent number
US04430339

Reaction notes

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