Formaldehyde → HCID 53780670, compound

HRID 1388146Notes

Reaction equation

HRID 1388146 reaction equation
[CH2:1]([O:3][C:4](=[O:23])[CH:5]([CH2:9][CH2:10][CH2:11][CH:12]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)[C:6](O)=O)[CH3:2].C=O.N1CCCCC1>N1C=CC=CC=1>[CH2:1]([O:3][C:4](=[O:23])[C:5](=[CH2:6])[CH2:9][CH2:10][CH2:11][CH:12]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)[CH3:2]

Participants

5

Reactant 3

HCID 712FormaldehydeHCID 8082PiperidineHCID 54367817HCID 54367817, compound

Product 1

HCID 53780670HCID 53780670, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

4.4 g of 5-cycloundecyl-2-methylenevaleric acid ethyl ester, in the form of a yellowish oil, which is purified by chromatography on silica gel (migrating agent: 95:5 petroleum ether/ethyl acetate), are obtained by the procedure described in Example (1b) from 7.6 g of (3-cycloundecylpropyl)-malonic acid ethyl ester, 0.84 g of paraformaldehyde, 7 ml of pyridine and 0.3 ml of piperidine.

Workup

  1. custom4.4 g of 5-cycloundecyl-2-methylenevaleric acid ethyl ester, in the form of a yellowish oil, which is purified by chromatography on silica gel (migrating agent: 95:5 petroleum ether/ethyl acetate)
  2. customare obtained by the procedure

Sources & evidence

ORD record
ord-bf885442bd644499ab72711da39d669c
Source dataset
uspto-grants-1984_02
Patent number
US04430339

Reaction notes

Loading…