m-Chloroperbenzoic acid → HCID 53843789, compound

HRID 1388150Notes

Reaction equation

HRID 1388150 reaction equation
[CH2:1]([O:3][C:4](=[O:19])[C:5](=[CH2:18])[CH2:6][CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)[CH3:2].ClC1C=CC=C(C(OO)=[O:28])C=1>C(Cl)Cl>[CH2:1]([O:3][C:4]([C:5]1([CH2:6][CH2:7][O:8][CH2:9][CH2:10][CH2:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]2)[CH2:18][O:28]1)=[O:19])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 54295183HCID 54295183, compound

Product 1

HCID 53843789HCID 53843789, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

6.8 g of the title compound, in the form of a colourless oil, which is purified by chromatography on silica gel (migrating agent: 90:10 petroleum ether/ethyl acetate) are obtained by the procedure described in Example (1a) from 12.4 g of 4-(3-cyclohexylpropyloxy)-2-methylenebutyric acid ethyl ester and 18.7 g of m-chloroperbenzoic acid in 250 ml of methylene chloride. Thin layer chromatography on silica gel with petroleum ether/ethyl acetate/glacial acetic acid 80:20:3: Rf =0.65.

Workup

  1. custom6.8 g of the title compound, in the form of a colourless oil, which is purified by chromatography on silica gel (migrating agent: 90:10 petroleum ether/ethyl acetate)
  2. customare obtained by the procedure

Sources & evidence

ORD record
ord-a4f3d07e1bd6462b81ae25c9f7f736bd
Source dataset
uspto-grants-1984_02
Patent number
US04430339

Reaction notes

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