Aluminium lithium hydride → HCID 20471774, compound

HRID 1388156Notes

Reaction equation

HRID 1388156 reaction equation
C([O:3][C:4](=O)[CH:5]([CH2:9][CH2:10][CH2:11][CH:12]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)C(O)=O)C.C(OC(=O)CCCCC1CCCCCC1)C.[H-].[Al+3].[Li+].[H-].[H-].[H-]>O1CCCC1>[CH:12]1([CH2:11][CH2:10][CH2:9][CH2:5][CH2:4][OH:3])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1

Participants

5

Reactant 3

HCID 21226445Aluminium lithium hydrideHCID 54419492HCID 54419492, compoundHCID 56611989HCID 56611989, compound

Product 1

HCID 20471774HCID 20471774, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The starting material 5-cycloheptylpentan-1-ol is obtained as follows: cycloheptylpropylmalonic acid ethyl ester is heated to 180° C. for one hour. The resulting 5-cycloheptylvaleric acid ethyl ester [bp 80°-82° C. at 0.008 mm Hg (1.0 Pa)] is reduced with lithium aluminum hydride in tetrahydrofuran to yield 5-cycloheptylpentan-1-ol [bp 92°-94° C. at 0.008 mm Hg (1.0 Pa)].

Sources & evidence

ORD record
ord-018cf7967570435aaa1607fa720e21fc
Source dataset
uspto-grants-1984_02
Patent number
US04430339

Reaction notes

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