1-Methylhomopiperazine → 87233-68-9

Participants

Reaction Steps

In the same manner as described in Example 1 using 1-[2-(alloyloxy)ethyl]-2-chlorobenzimidazole (4.00 g), N-methylhomopiperazine (4.00 g) and fumaric acid (2.58 g), there are obtained crude crystals, which are recrystallized from ethyl acetate-ethanol to give 1-[2-(allyloxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate (3.85 g) as colorless needles, m.p. 144.5°-146.5° C.

Provenance & Evidence