反应详情

p-Phenylphenol (VI) (1 kg, 5.88 mols) dissolved in ethanol (2 l) was fed into a 5 l autoclave, and hydrogenation reaction was carried out at a reaction temperature of 150° to 160° C. under a hydrogen pressure of 30 to 40 kg/cm2 using a developed Raney nickel (100 g) as catalyst. When 17.6 mols of hydrogen were absorbed, the reaction was stopped. After cooling, the catalyst was filtered off, and the filtrate was concentrated to remove ethanol. The resulting residue was dissolved in toluene. The toluene solution was washed a few times with 2 N--NaOH aqueous solution and further with water, and toluene was then removed by concentration of the solution. The resulting raw crystals were recrystallized from ethanol to obtain trans-4-phenylcyclohexanol (VII) (200 g) having a melting point of 118.4°-119.2° C.

1. customwas fed into a 5 l autoclave, and hydrogenation reaction
2. customwas carried out at a reaction temperature of 150° to 160° C. under a hydrogen
3. temperatureAfter cooling
4. filtrationthe catalyst was filtered off
5. concentrationthe filtrate was concentrated
6. customto remove ethanol
7. dissolutionThe resulting residue was dissolved in toluene
8. washThe toluene solution was washed a few times with 2 N
9. customNaOH aqueous solution and further with water, and toluene was then removed by concentration of the solution
10. customThe resulting raw crystals were recrystallized from ethanol