2-Bromo-1-(3,4-dichlorophenyl)ethanone → HCID 13186365, compound

HRID 1388300Notes

Reaction equation

HRID 1388300 reaction equation
[S:1]([CH2:5][C:6]([NH2:8])=[S:7])(=[O:4])(=[O:3])[NH2:2].[Cl:9][C:10]1[CH:11]=[C:12]([CH:17]=[CH:18][C:19]=1[Cl:20])[C:13](=O)[CH2:14]Br>C(O)C>[Cl:9][C:10]1[CH:11]=[C:12]([C:13]2[N:8]=[C:6]([CH2:5][S:1]([NH2:2])(=[O:4])=[O:3])[S:7][CH:14]=2)[CH:17]=[CH:18][C:19]=1[Cl:20]

Participants

4

Reactant 2

HCID 2447512-Bromo-1-(3,4-dichlorophenyl)ethanoneHCID 13186364Sulfamoylethanethioamide

Product 1

HCID 13186365HCID 13186365, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of sulfamoylthioacetamide (7.7 g., 0.05 mol) and 3,4-dichlorophenacyl bromide (13.4 g., 0.05 mol) in ethanol (50 ml) was heated at reflux for 2 hours. After cooling and filtration there was obtained 11.5 g. of the desired intermediate, m.p. 187°-190° C.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 2 hours
  3. temperatureAfter cooling
  4. filtrationfiltration there
  5. customwas obtained 11.5 g

Sources & evidence

ORD record
ord-4bc93edf8b17496d9f2f00da02e1d16c
Source dataset
uspto-grants-1984_02
Patent number
US04431652

Reaction notes

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