Oxalic Acid → HCID 20471303, compound

HRID 1388516Notes

Reaction equation

HRID 1388516 reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[Br:7][C:8]1[CH:19]=[CH:18][CH:17]=[CH:16][C:9]=1[CH2:10][N:11]1[CH:15]=[CH:14][N:13]=[CH:12]1>C(O)C>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[Br:7][C:8]1[CH:19]=[CH:18][CH:17]=[CH:16][C:9]=1[CH2:10][N:11]1[CH:15]=[CH:14][N:13]=[CH:12]1

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 132693191-[(2-Bromophenyl)methyl]-1H-imidazole

Product 1

HCID 20471303HCID 20471303, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of oxalic acid (0.14 g) in hot ethanol (10 ml) was added to a solution of 1-(2-bromobenzyl)imidazole (0.4 g) in hot ethanol (5 ml). After boiling for 10 minutes, the solution was evaporated under reduced pressure to afford a white solid. Recrystallisation of the solid from propan-2-ol gave 1-(2-bromobenzyl)imidazole hydrogen oxalate, m.p. 146°-147°.

Workup

  1. customthe solution was evaporated under reduced pressure
  2. customto afford a white solid
  3. customRecrystallisation of the solid from propan-2-ol

Sources & evidence

ORD record
ord-28788ca76f924c54b733c8a5c4f79006
Source dataset
uspto-grants-1984_02
Patent number
US04431815

Reaction notes

Loading…