Methanol → Ethyl 6-(3-chloro-4-fluorobenzyl)-4-methoxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate
Reaction equation
[CH3:27][Si:28]([CH:29]=[N+:30]=[N-:31])([CH3:32])[CH3:33].[CH3:37][OH:38].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:22])[c:8]3[c:9]([OH:21])[cH:10][n:11][c:12]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:13]3[CH2:14][CH2:15]2)[cH:23][cH:24][c:25]1[F:26].[Cl:34][CH2:35][Cl:36]>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:22])[c:8]3[c:9]([O:21][CH3:27])[cH:10][n:11][c:12]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:13]3[CH2:14][CH2:15]2)[cH:23][cH:24][c:25]1[F:26]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b1340e7ffc6e4177966314f90824b36a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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