HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichlorophenol → 5-(2,4-Dichlorophenoxy)-6-methoxy-4-methyl-8-nitroquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichlorophenol | HCID 8449 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 5-Chloro-6-methoxy-4-methyl-8-nitroquinoline | HCID 12049927 | — |
| Solvent | Glycol monoethyl ether | HCID 8076 | — |
| Product | 5-(2,4-Dichlorophenoxy)-6-methoxy-4-methyl-8-nitroquinoline | HCID 13004202 | — |
Reaction Steps
The title compound was prepared from 5-chloro-6-methoxy-4-methyl-8-nitroquinoline from Example 1 (15 g, 0.06 mol), 2,4-dichlorophenol (38 g, 0.23 mol), potassium hydroxide (13.2 g, 0.24 mol) and 2-ethoxyethanol (150 mL) as described in Example 1. The yield was 14.5 g (64%), mp 165.5°-168°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04431807 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-202121100b9f46e8903a24807ea3596b |
| Source note | uspto-grants-1984_02 |