Hydrochloric Acid → HCID 70513031, compound

HRID 1388677Notes

Reaction equation

HRID 1388677 reaction equation
[NH2:1][C:2]1[N:6]([CH:7]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH:8]([O:10][C:11](=[O:13])[CH3:12])[CH3:9])[CH:5]=[N:4][C:3]=1[C:20]([NH2:22])=[O:21].[ClH:23]>C(O)C>[ClH:23].[NH2:1][C:2]1[N:6]([CH:7]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])[CH:8]([O:10][C:11](=[O:13])[CH3:12])[CH3:9])[CH:5]=[N:4][C:3]=1[C:20]([NH2:22])=[O:21]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 56621955HCID 56621955, compound

Product 1

HCID 70513031HCID 70513031, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The product of step (a) (3.35 g) immediately above, was dissolved in ethanol (50 mls), cooled in an ice-bath, and one equivalent of 1 M hydrochloric acid was added. The solution was evaporated in vacuo and the residual oil re-dissolved in a minimum of ethanol at 30°. Sufficient ether was added to the stirred ethanolic solution to ensure complete precipitation and after stirring for 24 hours the title compound was obtained as a white solid (3.42 g; 49% overall), mp 179°-181° C.

Workup

  1. temperaturecooled in an ice-bath
  2. customThe solution was evaporated in vacuo
  3. dissolutionthe residual oil re-dissolved in a minimum of ethanol at 30°
  4. additionSufficient ether was added to the stirred ethanolic solution
  5. customprecipitation
  6. customwas obtained as a white solid (3.42 g; 49% overall), mp 179°-181° C.

Sources & evidence

ORD record
ord-ce9d1e38a28444d6a7c2e33906a57f5e
Source dataset
uspto-grants-1984_02
Patent number
US04432990

Reaction notes

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