HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 20470047, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1-(p-Methoxyphenyl)-2-propanone | HCID 31231 | — |
| Reactant | 2-Amino-1-(1-benzofuran-2-yl)ethan-1-ol | HCID 12814357 | — |
| Reactant | Diethylether hexane | HCID 21584099 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20470047 | HCID 20470047 | — |
Reaction Steps
This compound was prepared in an identical manner to the compound described in Example 2 using 2-(2-benzofuranyl)-2-hydroxyethanamine (1.65 g) and 1-(4-methoxyphenyl)propan-2-one (1.53 g). Chromatography of the residual oil on Kieselgel 60 (4% methanol in dichloromethane) gave the title compound, m.p. 75°-85° (Et2O-hexane) as a 44:56 mixture of diastereoisomers.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04432993 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-bb6872caa1094bfd9808ecc701273d86 |
| Source note | uspto-grants-1984_02 |