1,2-Dinitrobenzene → ethyl P-methyl-2-nitrophenylphosphinate

HRID 1388771Notes

Reaction equation

HRID 1388771 reaction equation
[N+]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N+:10]([O-:12])=[O:11])([O-])=O.[CH3:13][P:14]([O:18]CC)[O:15][CH2:16][CH3:17]>C(#N)C>[CH3:13][P:14]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[N+:10]([O-:12])=[O:11])(=[O:18])[O:15][CH2:16][CH3:17]

Participants

4

Reactant 2

HCID 107071,2-DinitrobenzeneHCID 85063Diethyl methylphosphonite

Product 1

HCID 13292704ethyl P-methyl-2-nitrophenylphosphinate

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of 1,2-dinitrobenzene (2.48 mmol), diethyl methylphosphonite (3.72 mmol) and acetonitrile (3 ml) is stirred at RT overnight. The reaction is concentrated to dryness, and the residue is purified by preparative thin layer chromatography (TLC) to yield ethyl P-methyl-2-nitrophenyl-phosphinate.

Workup

  1. concentrationThe reaction is concentrated to dryness
  2. customthe residue is purified by preparative thin layer chromatography (TLC)

Sources & evidence

ORD record
ord-68f7e23fd62847efa05a5cc2e5a98d28
Source dataset
uspto-grants-1984_02
Patent number
US04433149

Reaction notes

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