1,2-Dinitrobenzene → ethyl P-methyl-2-nitrophenylphosphinate

Participants

Reaction Steps

A mixture of 1,2-dinitrobenzene (2.48 mmol), diethyl methylphosphonite (3.72 mmol) and acetonitrile (3 ml) is stirred at RT overnight. The reaction is concentrated to dryness, and the residue is purified by preparative thin layer chromatography (TLC) to yield ethyl P-methyl-2-nitrophenyl-phosphinate.

Provenance & Evidence