Sodium Hydroxide → HCID 3062094, compound

Participants

Reaction Steps

The operation is as in Example 18, starting from 13.5 g of 1-(7-chloro-2-phenyl-4-quinolyl)-2-(4-piperidyl)-ethanone prepared as indicated in Example 10, 6 g of 98% hydrazine hydrate and 2.4 g of sodium hydroxide in 200 ml of diethylene glycol. 4.5 g of 7-chloro-2-phenyl-4-[2-(4-piperidyl)-ethyl]-quinoline are obtained, the monohydrochloride of which, formed by the action of hydrochloric acid in isopropanol, melts at 195° C.

Provenance & Evidence