HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,4,5-Pentafluoro-6-pentafluorophenoxybenzene → HCID 178462347, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,4,5-Pentafluoro-6-pentafluorophenoxybenzene | HCID 631653 | — |
| Reactant | N-tert-Butoxycarbonyl-L-threonine | HCID 2724766 | — |
| Reactant | HCID 178512872 | HCID 178512872 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 178462347 | HCID 178462347 | — |
Reaction Steps
2.18 g (4.1 mmol) of Nε -benzyloxycarbonyl-lysyl-prolyl-arginine IV in 30 ml of water are added, under stirring, to a solution of 2.10 g (5.3 mmol) of pentafluorophenyl ether of tert.butyloxycarbonyl-threonine in 70 ml of dioxane. Then the reaction mixture is treated following the procedure described for the synthesis of compound III. The yield of the desired product--tert.butyloxycarbonyl-threonyl-Nε -benzyloxycarbonyl-lysyl-prolyl-arginine is 2.65 g (188%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04434095 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-dbbdc36d147e49819d2eb286520328cd |
| Source note | uspto-grants-1984_02 |