HCID 13132221, compound → HCID 12553985, compound

HRID 1388893Notes

Reaction equation

HRID 1388893 reaction equation
N([C:3]1[C:8]([N+:9]([O-:11])=[O:10])=[C:7]([O:12][CH3:13])[N:6]=[CH:5][N:4]=1)N>CO.[Ag-]=O>[CH3:13][O:12][C:7]1[C:8]([N+:9]([O-:11])=[O:10])=[CH:3][N:4]=[CH:5][N:6]=1

Participants

4

Reactant 1

HCID 13132221HCID 13132221, compound

Product 1

HCID 12553985HCID 12553985, compoundYield 89.5%

Reagents, catalysts & solvents 2

HCID 178418778HCID 178418778, compoundCatalystHCID 887MethanolSolvent

Procedure

14 g 4-hydrazino-6-methoxy-5-nitropyrimidine are dissolved in 3.6 liters of methanol and stirred for 10 hours at 40° C. with 61.9 g of freshly prepared silver (I) oxide. Then the mixture is filtered and the solution evaporated. 10.5 g 4-methoxy-5-nitropyrimidine with a melting point of 193° to 195° C. is obtained.

Workup

  1. filtrationThen the mixture is filtered
  2. customthe solution evaporated

Sources & evidence

ORD record
ord-a94305473fa0402984c79d8c5af02281
Source dataset
uspto-grants-1984_02
Patent number
US04434167

Reaction notes

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