HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 12553985, compound → 4-Methoxypyrimidin-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 12553985 | HCID 12553985 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Methoxypyrimidin-5-amine | HCID 13277465 | 99.2% |
Reaction Steps
10 g 4-methoxy-5-nitropyrimidine in 500 ml methanol are hydrated for 2.5 hours at 2 bar in the presence of 4.5 g Raney nickel. After filtration, the solution is concentrated. 8.0 g 5-amino-4-methoxypyrimidine having a melting point of 71° to 74° C. are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04434167 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-58999e9308004d959a9a6d7a0a7620e1 |
| Source note | uspto-grants-1984_02 |