反应详情

温度

110 °C

A mixture of 13.6 g of o-anisaldehyde, 13.4 g of ethyl 2-mercaptopropionate and 6 g of ammonium carbonate in 250 ml of toluene was refluxed at 110° C. for 2 hours in a flask provided with a Dean-Stark apparatus while removing the distilled water. The crystals which separated out after leaving the reaction mixture for a night were collected by filtering and recrystallized from hot benzene to obtain the object, colourless prisms melting at 187° to 187.5° C. in an amount of 21 g corresponding to a yield of 94%.

1. customprovided with a Dean-Stark apparatus
2. customwhile removing the distilled water
3. customThe crystals which separated out
4. customafter leaving the reaction mixture for a night
5. customwere collected
6. filtrationby filtering
7. customrecrystallized from hot benzene