HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-(p-Chlorobenzoyl)-2-hydroxycarbonyl-4-methylthio-1-methylpyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-(p-Chlorobenzoyl)-2-methoxycarbonyl-4-methylthio-1-methylpyrrole | HCID 20469097 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(p-Chlorobenzoyl)-2-hydroxycarbonyl-4-methylthio-1-methylpyrrole | HCID 20469082 | — |
Reaction Steps
5-(p-Chlorobenzoyl)-2-methoxycarbonyl-4-methylthio-1-methylpyrrole (39 mg) is dissolved in 1 ml of warm ethanol and 0.5 ml of 2.5 N sodium hydroxide is added. After standing at room temperature for 30 minutes under nitrogen, 0.7 ml of 2.5 N hydrochloric acid is aded. The resulting precipitate is filtered, washed and dried in vacuo to yield the crude 5-(p-chlorobenzoyl)-2-hydroxycarbonyl-4-methylthio-1-methylpyrrole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04434175 |
| Source dataset | uspto-grants-1984_02 |
| ORD ID | ord-969e2f61c6004931834e3dd1e2667f53 |
| Source note | uspto-grants-1984_02 |