反应详情

5-(p-Chlorobenzoyl)-2-methoxycarbonyl-4-methylthio-1-methylpyrrole (39 mg) is dissolved in 1 ml of warm ethanol and 0.5 ml of 2.5 N sodium hydroxide is added. After standing at room temperature for 30 minutes under nitrogen, 0.7 ml of 2.5 N hydrochloric acid is aded. The resulting precipitate is filtered, washed and dried in vacuo to yield the crude 5-(p-chlorobenzoyl)-2-hydroxycarbonyl-4-methylthio-1-methylpyrrole.

1. filtrationThe resulting precipitate is filtered
2. washwashed
3. customdried in vacuo