Sulfuryl chloride → HCID 19991371, compound

HRID 1388992Notes

Reaction equation

HRID 1388992 reaction equation
S(Cl)(Cl)(=O)=O.[Cl:6][C:7]1[CH:8]=[C:9]([N:14]2[C:18](=O)[C:17]([CH3:20])=[CH:16][S:15]2)[CH:10]=[CH:11][C:12]=1[Cl:13]>C(Cl)CCl>[CH3:20][C:17]1[CH2:16][S:15][N:14]([C:9]2[CH:10]=[CH:11][C:12]([Cl:13])=[C:7]([Cl:6])[CH:8]=2)[CH:18]=1

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 130137652-(3,4-Dichlorophenyl)-4-methyl-3(2H)-isothiazolone

Product 1

HCID 19991371HCID 19991371, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent2×

Procedure

Dithio-(3',4'-dichloro)-diisobutyranilide, 12.8 g. (0.0234 mole), was slurried in 250 ml. of ethylene dichloride, and a solution of 9.5 g. (0.0702 mole) of sulfuryl chloride in 25 ml. of ethylene dichloride was added dropwise at 25°-30° C. over one hour. The slurry was stirred overnight to insure completion of the reaction and then filtered to give 8.6 g. of gray 2-(3,4-dichlorophenyl)-4-methyl-3-isothiazolone, m.p. 160°-161° C. The product was crystallized from ethyl acetate to give a m.p. of 161°-163° C.

Workup

  1. customcompletion of the reaction
  2. filtrationfiltered
  3. customto give 8.6 g
  4. customThe product was crystallized from ethyl acetate
  5. customto give a m.p. of 161°-163° C.

Sources & evidence

ORD record
ord-dbc5cd12ea46432cb17edbc8249efda0
Source dataset
uspto-grants-1981_01
Patent number
US04243403

Reaction notes

Loading…