Sodium Hydroxide → HCID 23709239, compound

HRID 1389074Notes

Reaction equation

HRID 1389074 reaction equation
[F:1][C:2]1[CH:10]=[C:9]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[OH-].[Na+:29]>C(O)C.O>[F:1][C:2]1[CH:10]=[C:9]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH:8]=[CH:7][C:3]=1[C:4]([O-:6])=[O:5].[Na+:29]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 205364112-Fluoro-4-(hexadecylamino)benzoic acid

Product 1

HCID 23709239HCID 23709239, compound

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

A mixture of 3.62 g. of 2-fluoro-4-(hexadecylamino)-benzoic acid and 25 ml of ethanol-water (9:1) containing 0.400 g of sodium hydroxide is stirred for 4 hours. The mixture is filtered and the residue washed with 10 ml of ethanol-water (9:1) and dried, in vacuo, over P2O5 for 24 hours to yield sodium 2-fluoro-4-(hexadecylamino)benzoate as a white solid.

Workup

  1. additionA mixture of 3.62 g
  2. filtrationThe mixture is filtered
  3. washthe residue washed with 10 ml of ethanol-water (9:1)
  4. dry with materialdried, in vacuo, over P2O5 for 24 hours

Sources & evidence

ORD record
ord-3e64cbcfb8be4c37af7b3ec13352b47a
Source dataset
uspto-grants-1981_01
Patent number
US04243609

Reaction notes

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