Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1389154Generated: October 30, 2026

N-Methylbenzylamine → N-benzyl-N-methylpiperidine-4-carboxamide

https://huagongshe.com/reaction/1389154

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-MethylbenzylamineHCID 7669—
ReactantBenzyl 4-(chlorocarbonyl)piperidine-1-carboxylateHCID 2776270—
ProductN-benzyl-N-methylpiperidine-4-carboxamideHCID 5103038—

Reaction Steps

This compound was prepared similarly to Preparation C starting from 1-benzyloxycarbonylpiperidine-4-carboxylic acid chloride and N-methylbenzylamine, and was used directly in Example 10. This intermediate was characterised as the hydrochloride salt, m.p. 175°-176°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04243666
Source datasetuspto-grants-1981_01
ORD IDord-0399a0cb0319432c8d68d929a598f5c5
Source noteuspto-grants-1981_01