HuagongsheHuagongshe Chemistry Print Report · For research reference only
Epichlorohydrin → HCID 20298520, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Epichlorohydrin | HCID 7835 | — |
| Reactant | 2-Cyclohexylethylamine | HCID 20509 | — |
| Reactant | 4-(Propan-2-ylsulfanyl)phenol | HCID 13058453 | — |
| Product | HCID 20298520 | HCID 20298520 | 18% |
Reaction Steps
Reaction of the epichlorohydrin derivative of 4-(isopropylthio)phenol (5.0 g., 0.022 mole) with cyclohexylethylamine (3.3 g., 0.026 mole) according to the procedure of Example 2(b) and crystallization of the crude product from isopropyl alcohol affords an 18% yield of analytically pure 1-[(2-cyclohexylethyl)amino]-3-[4-[(1-methylethyl)thio]phenoxy]-2-propanol hydrochloride, m.p. 180°-182° (corr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04243681 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-f51a32b033d74ebcb3cf616567827ee1 |
| Source note | uspto-grants-1981_01 |