HuagongsheHuagongshe Chemistry Print Report · For research reference only
Epichlorohydrin → HCID 20298496, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Epichlorohydrin | HCID 7835 | — |
| Reactant | 4-cyclohexylbutan-1-amine | HCID 3058956 | — |
| Reactant | 4-(Propan-2-ylsulfanyl)phenol | HCID 13058453 | — |
| Product | HCID 20298496 | HCID 20298496 | 11.4% |
Reaction Steps
Reaction of the epichlorohydrin derivative of 4-(isopropylthio)phenol (9.0 g., 0.04 mole) with cyclohexylbutylamine (6.7 g., 0.043 mole) according to procedure of Example 2(b) and crystallization of the crude product from ethanol affords an 11.4% yield of analytically pure 1-[(4-cyclohexylbutyl)amino]-3-[4-[(1-methylethyl)thio]phenoxy]-2-propanol hydrochloride, m.p. 179° with prior softening from 118°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04243681 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-f2f3998489404d2da312a5792d4e00b2 |
| Source note | uspto-grants-1981_01 |