Phenethylamine → HCID 20298685, compound

HRID 1389255Notes

Reaction equation

HRID 1389255 reaction equation
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[C:5]([O:11][CH2:12][CH2:13][CH2:14][N:15]2[CH2:20][CH2:19][O:18][CH2:17][CH2:16]2)[CH:4]=1.[CH2:21]([NH2:29])[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>C1(C)C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=[N:29][CH2:21][CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[C:5]([CH:4]=1)[O:11][CH2:12][CH2:13][CH2:14][N:15]1[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1

Participants

4

Reactant 2

HCID 1001PhenethylamineHCID 202986814-Methoxy-2-[3-(4-morpholinyl)propoxy]benzaldehyde

Product 1

HCID 20298685HCID 20298685, compoundYield 81.4%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

4-Methoxy-2-[3-(4-morpholinyl)propoxy]benzaldehyde (29.7 g) and 13.0 g of phenethylamine are reacted in 110 ml of toluene following the procedure described in Example 1B, yielding 33.1 g of the title compound, boiling point 240°-245° C. at 0.1-0.2 mm of Hg.

Sources & evidence

ORD record
ord-3151c17e22aa4d7ea4c49dfcc8f94eb9
Source dataset
uspto-grants-1981_01
Patent number
US04243804

Reaction notes

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