Methanol → N-hydroxy-1-methyl-2-[(4-phenylpiperidin-1-yl)carbonyl]-5-(pyridin-4-yloxy)piperidine-3-carboxamide

HRID 138940Notes

Reaction equation

HRID 138940 reaction equation
[CH3:42][OH:43].[F:33][C:34]([F:35])([F:36])[C:37]([OH:38])=[O:39].[H:40][H:41].[OH:1][NH:2][C:3](=[O:4])[CH:5]1[CH:6]([C:19](=[O:20])[N:21]2[CH2:22][CH2:23][C:24]([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)=[CH:25][CH2:26]2)[N:7]([CH3:18])[CH2:8][CH:9]([O:11][c:12]2[cH:13][cH:14][n:15][cH:16][cH:17]2)[CH2:10]1>>[OH:1][NH:2][C:3](=[O:4])[CH:5]1[CH:6]([C:19](=[O:20])[N:21]2[CH2:22][CH2:23][CH:24]([c:27]3[cH:28][cH:29][cH:30][cH:31][cH:32]3)[CH2:25][CH2:26]2)[N:7]([CH3:18])[CH2:8][CH:9]([O:11][c:12]2[cH:13][cH:14][n:15][cH:16][cH:17]2)[CH2:10]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6422Trifluoroacetic acidHCID 145728876N-hydroxy-1-methyl-2-(4-phenyl-3,6-dihydro-2H-pyridine-1-carbonyl)-5-pyridin-4-yloxypiperidine-3-carboxamideHCID 178418361HCID 178418361, compound

Product 1

HCID 131737176N-hydroxy-1-methyl-2-[(4-phenylpiperidin-1-yl)carbonyl]-5-(pyridin-4-yloxy)piperidine-3-carboxamide

Sources & evidence

ORD record
ord-ccfab21f16994c4990bc11d6a9516023
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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