HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20296596, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 8-[2-Hydroxy-3-(2-methoxyphenoxy)propyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one | HCID 13016648 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 20296596 | HCID 20296596 | — |
Reaction Steps
To a solution of 1 g of 8-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one in 5 ml methanol is added 10 ml, 3% hydrochloric acid in methanol. Addition of 200 ml diethyl ether followed by filtration affords 8-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride, mp indefinite.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04244961 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-438539056a1f44889abdbee608915353 |
| Source note | uspto-grants-1981_01 |