Carbon Disulfide → 1-(2-Hydroxyethyl)-4-phenylimidazolidine-2-thione
Reaction equation
[NH2:1][CH:2]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:3][NH:4][CH2:5][CH2:6][O:7]C.[C:15](=S)=[S:16]>ClCC(Cl)(Cl)Cl>[OH:7][CH2:6][CH2:5][N:4]1[CH2:3][CH:2]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[NH:1][C:15]1=[S:16]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 120 °C
Procedure
The methoxyethylamine product of Example IV in the amount of 4.5 g is dissolved in 20 ml of tetrachloroethane, and is stirred with 2 ml carbon disulfide at room temperature for one hour. The resulting slurry is then slowly heated to 120° C. and maintained at that temperature for four hours.
Workup
- temperaturemaintained at that temperature for four hours
Sources & evidence
- ORD record
- ord-77229deeb7754368a97c1003b413c1f5
- Source dataset
- uspto-grants-1981_01
- Patent number
- US04245102
Reaction notes
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