Sodium Hydroxide → HCID 178526276, compound

HRID 1389572Notes

Reaction equation

HRID 1389572 reaction equation
Br.[Cl:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([Cl:9])[C:4]=1[N:10]=[C:11]1[NH:15][CH2:14][CH2:13][N:12]1[OH:16].[OH-].[Na+]>O>[Cl:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([Cl:2])[C:4]=1[N:10]=[C:11]1[NH:15][CH2:14][CH2:13][N:12]1[OH:16]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178419752HCID 178419752, compound

Product 1

HCID 178526276HCID 178526276, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.6 g. of 2-[(2,6-dichlorophenyl)imino]-1-hydroxyimidazolidine hydrobromide is dissolved in a little water and the pH is adjusted to 10 with 1 N caustic soda solution. The precipitate formed is extracted with methylene chloride. The organic extracts are dried over sodium sulfate and evaporated to dryness. The residue is recrystallized from acetonitrile, whereupon 2-[(2,6-dichlorophenyl)imino]-1-hydroxyimidazolidine, m.p. 215° (decomp.) is obtained.

Workup

  1. customThe precipitate formed
  2. extractionis extracted with methylene chloride
  3. dry with materialThe organic extracts are dried over sodium sulfate
  4. customevaporated to dryness
  5. customThe residue is recrystallized from acetonitrile, whereupon 2-[(2,6-dichlorophenyl)imino]-1-hydroxyimidazolidine
  6. customm.p. 215° (decomp.) is obtained

Sources & evidence

ORD record
ord-6620221c134448888c811bd3bfdbcad2
Source dataset
uspto-grants-1981_01
Patent number
US04244957

Reaction notes

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