反应详情

32 g of 2-[2'-(2-methoxyethoxy)-5'-nitrobenzenesulfonamido]-4-hexadecyloxy-5-methylphenol prepared as described in Step (b) above, 24 g of iron powder (Fe2O3), 12 g of Fe3O4, 0.6 g of ammonium chloride and 25 ml of water were added to 300 ml of isopropyl alcohol and the mixture was refluxed on a steam bath with stirring for 1 hour. After completion of the reaction, the mixture was filtered while hot and the filtrate was cooled with ice. The crystals thus-precipitated were recovered by filtration, washed with 50 ml of isopropyl alcohol and air-dried. Yield: 23 g; Melting Point: 142° to 144° C.

1. temperaturethe mixture was refluxed on a steam bath
2. customAfter completion of the reaction
3. filtrationthe mixture was filtered while hot and the filtrate
4. temperaturewas cooled with ice
5. customThe crystals thus-precipitated
6. filtrationwere recovered by filtration
7. washwashed with 50 ml of isopropyl alcohol
8. customair-dried