反应详情

To a stirred mixture of 43.8 parts of 2,6-dichlorobenzaldehyde, 41 parts of 2-naphthalenamine and 500 parts of glacial acetic acid is added dropwise a solution of 20.3 parts of potassium cyanide in 35 parts of water. The whole is stirred for 40 hours at room temperature. The precipitated product is filtered off, washed on the filter with glacial acetic acid, with 2-propanol and petrleum ether, and dried, yielding 60 parts of 2,6-dichloro-α-[(2-naphthalenyl)amino]benzeneacetonitrile; mp. 94.8° C.

1. filtrationThe precipitated product is filtered off
2. washwashed on the
3. filtrationfilter with glacial acetic acid, with 2-propanol and petrleum ether
4. customdried