Sodium Hydroxide → HCID 23686191, compound

Participants

Reaction Steps

A mixture of 8.62 parts of 2,3,6-trichloro-α-[(2-methylphenyl)amino]benzeneacetic acid, 25 parts of a sodium hydroxide solution 1 M in water and 100 parts of distilled water is stirred for 30 minutes at room temperature. The resulting solution is evaporated to dry, methylbenzene is added and evaporation is continued. The residue is suspended in 2,2'-oxybispropane. The product is filtered off and crystallized from acetonitrile, yielding 7 parts of sodium 2,3,6-trichloro-α-[(2-methylphenyl)amino]benzeneacetate; mp. 203.1° C.

Provenance & Evidence