Acetone → HCID 20294102, compound

HRID 1389950Notes

Reaction equation

HRID 1389950 reaction equation
N[C:2]1[CH:3]=[C:4]([NH:8][C:9]([N:11]([CH3:13])[CH3:12])=[O:10])[CH:5]=[CH:6][CH:7]=1.C[C:15]([CH3:17])=O.C([N:20]([CH2:23][CH3:24])[CH2:21]C)C.C(C1C(Cl)=C(C([O-])=O)[S:32]C=1)(C)(C)C>O>[CH2:23]([NH:20][C:21]([C:2]1[CH:3]=[C:4]([NH:8][C:9]([N:11]([CH3:13])[CH3:12])=[O:10])[CH:5]=[CH:6][CH:7]=1)=[S:32])[CH2:24][CH2:15][CH3:17]

Participants

6

Reactant 4

HCID 180AcetoneHCID 8471TriethylamineHCID 181644Urea, 3-(3-aminophenyl)-1,1-dimethyl-HCID 86737456HCID 86737456, compound

Product 1

HCID 20294102HCID 20294102, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Ten and eight-tenths grams of 1(3'-amino phenyl) 3,3-dimethyl urea is dissolved in 100 ml. of acetone and 7.1 g. of triethylamine is added. Nine and two-tenths grams of t-butylchlorothiolformate is added dropwise with stirring. When reaction is complete, the mixture is poured into water and a viscious oil precipitated. The product is taken up in methylene dichloride and washed with dilute HCl and dried over magnesium sulfate. The methylene chloride is taken off under vacuum, leaving a solid foam. There is obtained 15.9 g., m.p. 68°-71° C., of the title compound.

Workup

  1. customWhen reaction
  2. customa viscious oil precipitated
  3. washwashed with dilute HCl
  4. dry with materialdried over magnesium sulfate
  5. customleaving a solid foam
  6. customThere is obtained 15.9 g

Sources & evidence

ORD record
ord-b7fe76ecfd604fee8b1d2ffa55e65168
Source dataset
uspto-grants-1981_01
Patent number
USRE030495

Reaction notes

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