HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178522648, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | HCID 178509300 | HCID 178509300 | — |
| Reactant | HCID 178524061 | HCID 178524061 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178522648 | HCID 178522648 | — |
Reaction Steps
From 4,9-dihydro-9-oxo-5-(tetrahydro-2-thienyl)pyrazolo[5,1-b]quinazoline-2-carboxylic acid, compound with methanol (1:1) (0.40 g; 1.3 mmole), DMF (20 ml); 1,1' carbonyl-diimidazole (0.5 g; 3.1 mmole) and 5-amino-1H-tetrazole, monohydrate (0.131 g; 1.3 mmole), following the procedure of Example 3, there is obtained 4,9-dihydro-9-oxo-5-(tetrahydro-2-thienyl)-N-1H-tetrazol-5-yl-pyrazolo[5,1-b]quinazoline-2-carboxamide (70 mg); mp>230° (d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04247555 |
| Source dataset | uspto-grants-1981_01 |
| ORD ID | ord-b393faec401340f487e3a19106d1a494 |
| Source note | uspto-grants-1981_01 |