Benzenesulfonyl chloride → HCID 53902387, compound

HRID 1390043Notes

Reaction equation

HRID 1390043 reaction equation
[OH:1][C:2]1[CH:6]=[C:5]([CH2:7][CH2:8][C:9]([O:11][CH:12]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[S:10])[O:4][N:3]=1.[C:25]1([S:31](Cl)(=[O:33])=[O:32])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>C(N(CC)CC)C>[C:25]1([S:31]([O:1][C:2]2[CH:6]=[C:5]([CH2:7][CH2:8][C:9]([O:11][CH:12]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)=[S:10])[O:4][N:3]=2)(=[O:33])=[O:32])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

4

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 178516036HCID 178516036, compound

Product 1

HCID 53902387HCID 53902387, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

This benzhydryl 3-hydroxyisoxazol-5-ylmethylthioacetate was reacted with benzenesulphonyl chloride in the presence of triethylamine to give benzhydryl 3-benzenesulphonyloxyisoxazol-5-ylmethylthioacetate, which was treated with trifluoroacetic acid to afford the title compound as crystals.

Sources & evidence

ORD record
ord-0061cf6ccda84c449de811ec19d8327e
Source dataset
uspto-grants-1981_01
Patent number
US04247548

Reaction notes

Loading…