Methyl cyanoacetate → HCID 20294992, compound

HRID 1390101Notes

Reaction equation

HRID 1390101 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7](Cl)[N:6]=[C:5](Cl)[N:4]=1.[C:11]([CH2:13][C:14]([O:16][CH3:17])=[O:15])#[N:12].[H-].[Na+]>>[C:14]([CH:13]([C:11]#[N:12])[C:5]1[N:6]=[C:7]([CH:13]([C:14]([O:16][CH3:17])=[O:15])[C:11]#[N:12])[N:8]=[C:3]([O:2][CH3:1])[N:4]=1)([O:16][CH3:17])=[O:15]

Participants

4

Reactant 3

HCID 7747Methyl cyanoacetateHCID 192672,4-Dichloro-6-methoxy-3,5-triazineHCID 24758Sodium hydride

Product 1

HCID 20294992HCID 20294992, compoundYield 82%

Procedure

The preparation was carried out in the same way as indicated in Example II. 2.70 g (0.015 moles) of 2-methoxy-4,6-dichloro-s-triazine were converted with the reaction product of 5.95 g (0.06 moles) of methyl cyanoacetate and 1.44 g (0.06 moles) of sodium hydride. After extraction with methanol and petroleum ether (boiling point 40°-60° C.) 3.74 g of 2,4-di-(carbomethoxycyanomethyl)-6-methoxy-s-triazine were obtained in 82% yield. The UV absorption maxima were at' ##EQU18##

Workup

  1. extractionAfter extraction with methanol and petroleum ether (boiling point 40°-60° C.) 3.74 g of 2,4-di-(carbomethoxycyanomethyl)-6-methoxy-s-triazine
  2. customwere obtained in 82% yield
  3. customThe UV absorption maxima

Sources & evidence

ORD record
ord-75cdbb1c215e4668914013271974762f
Source dataset
uspto-grants-1981_01
Patent number
US04247692

Reaction notes

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