HCID 22748383, compound → HCID 22748363, compound

HRID 1390182Notes

Reaction equation

HRID 1390182 reaction equation
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([O:12][CH2:13][CH2:14][O:15][C:16]2[CH:21]=[CH:20][C:19]([N+:22]([O-])=O)=[CH:18][CH:17]=2)=[CH:4][C:3]=1[C:25]([NH:27][CH2:28][CH2:29][CH2:30][O:31][C:32]1[CH:37]=[CH:36][C:35]([C:38]([CH2:41][CH3:42])([CH3:40])[CH3:39])=[CH:34][C:33]=1[C:43]([CH2:46][CH3:47])([CH3:45])[CH3:44])=[O:26]>C(O)C.[C].[Pd]>[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([O:12][CH2:13][CH2:14][O:15][C:16]2[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=2)=[CH:4][C:3]=1[C:25]([NH:27][CH2:28][CH2:29][CH2:30][O:31][C:32]1[CH:37]=[CH:36][C:35]([C:38]([CH2:41][CH3:42])([CH3:39])[CH3:40])=[CH:34][C:33]=1[C:43]([CH2:46][CH3:47])([CH3:45])[CH3:44])=[O:26]

Participants

4

Reactant 1

HCID 22748383HCID 22748383, compound

Product 1

HCID 22748363HCID 22748363, compound

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

By dispersing 6.4 g of Intermediate 3 in 64 ml of ethanol and then hydrogenating the intermediate in an autoclave using a palladium-carbon catalyst, the desired product was obtained. The solvent used for the recrystallization was ethanol. The melting point of the product was 147-149° C.

Sources & evidence

ORD record
ord-886693f544df4c5c9005bbb61954e989
Source dataset
uspto-grants-1979_02
Patent number
US04138258

Reaction notes

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