alpha-Benzamido(2,3-dihydro-5-benzofuranyl)acetic acid → 2-Amino-2-(2,3-dihydro-1-benzofuran-5-yl)acetic acid

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Reaction Steps

The α-benzamido(2,3-dihydro-5-benzofuranyl)acetic acid (100 mg) is dissolved in 20 ml of methanol and 40 ml of water. Then 20 mg of Pd/C catalyst is added and the mixture subjected to 40 pounds/in2 of hydrogen pressure for 4 hours. The mixture is filtered to remove the solid and the methanol is evaporated to give the title compound in about 60% yield.

Provenance & Evidence