Sodium Bicarbonate → HCID 23666533, compound

HRID 1390300Notes

Reaction equation

HRID 1390300 reaction equation
C(=O)([O-])O.[Na+:5].[CH2:6]([N:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16]([CH:23]([CH3:27])[C:24]([OH:26])=[O:25])=[CH:15][C:14]1=[O:28])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>O>[CH2:6]([N:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16]([CH:23]([CH3:27])[C:24]([O-:26])=[O:25])=[CH:15][C:14]1=[O:28])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1.[Na+:5]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 12802755HCID 12802755, compound

Product 1

HCID 23666533HCID 23666533, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

An aqueous solution (1.63 ml.) of 1M-sodium hydrogen carbonate was added to a stirred suspension of powdered α-(1-benzyl-1,2-dihydro-2-oxoquinol-4-yl)propionic acid (0.50 g.) in distilled water (3.37 ml.), and the mixture was stirred overnight, at ambient temperature. The solid which had formed was separated and dried in vacuo over phosphorus pentoxide to give sodium α-(1-benzyl-1,2-dihydro-2-oxoquinol-4-yl)propionate (0.52 g.) as its monohydrate (m.p., indefinite; C19H16NO3.H2O requires: C, 65.5; H, 4.9; N, 3.8; found: C, 65.7; H, 5.2; N, 4.0).

Workup

  1. customThe solid which had formed
  2. customwas separated
  3. dry with materialdried in vacuo over phosphorus pentoxide

Sources & evidence

ORD record
ord-f30f6843302a41f3945352e428c30b98
Source dataset
uspto-grants-1979_02
Patent number
US04138490

Reaction notes

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