Potassium Hydroxide → HCID 22748753, compound

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Reaction Steps

Dissolve 3.8 g. of 4-(1,1-diphenylpropyl)-picolinamide in 50 ml. of ethanol, add 100 ml. of 10% aqueous potassium hydroxide and heat the resulting mixture at reflux overnight. Remove the ethanol under reduced pressure, add water to the residue and adjust to about pH 5 with 10% aqueous hydrochloric acid. Filter the resulting solid and crystallize the precipitate from ethanol to obtain thereby the compound of this example, yield -- 1.6 g., m.p. 191°-193° C.

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