Cysteamine → HCID 12906353, compound

HRID 1390677Notes

Reaction equation

HRID 1390677 reaction equation
[C:1]([CH:3]1[CH:12]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:18]=3[CH:5]([C:6]3[C:11]2=[CH:10][CH:9]=[CH:8][CH:7]=3)[CH2:4]1)#[N:2].N[CH2:20][CH2:21][SH:22]>>[S:22]1[CH2:21][CH2:20][N:2]=[C:1]1[CH:3]1[CH:12]2[C:11]3[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=3[CH:5]([C:18]3[C:13]2=[CH:14][CH:15]=[CH:16][CH:17]=3)[CH2:4]1

Participants

3

Reactant 2

HCID 6058CysteamineHCID 2403063008-09-1

Product 1

HCID 12906353HCID 12906353, compoundYield 77.6%

Conditions

Temperature
130 °C

Procedure

A mixture of 11-cyano-9,10-dihydro-9,10-ethanoanthracene (4.6 g) and 2-aminoethanethiol (2.0 g) is stirred at 130° C. for 4 hours. The reaction mixture is recrystallized from ethanol to give 11-(2-thiazolin-2-yl)-9,10-dihydro-9,10-ethanoanthracene (4.5 g) as crystals melting at 160 to 161° C. IR (KBr), 1619 cm-1 (S--C=N).

Workup

  1. customThe reaction mixture is recrystallized from ethanol

Sources & evidence

ORD record
ord-c57b8edb294c4b78b51e785958e75cac
Source dataset
uspto-grants-1979_02
Patent number
US04139711

Reaction notes

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