Trifluoroacetic acid → HCID 178514771, compound

HRID 1390716Notes

Reaction equation

HRID 1390716 reaction equation
C([O:5][C:6]([C:8]1[N:13]2[C:14](=[O:28])[CH:15]([NH:16][C:17](=[O:27])[CH2:18][S:19]([CH2:22][C:23]([F:26])([F:25])[F:24])(=[O:21])=[O:20])[C@H:12]2[S:11][CH2:10][C:9]=1[CH:29]([S:36][C:37]1[NH:41][N:40]=[N:39][N:38]=1)[CH2:30][CH2:31][S:32](=[O:35])(=[O:34])[NH2:33])=[O:7])(C)(C)C.FC(F)(F)C(O)=O>C(#N)C>[F:26][C:23]([F:24])([F:25])[CH2:22][S:19]([CH2:18][C:17]([NH:16][CH:15]1[C:14](=[O:28])[N:13]2[C:8]([C:6]([OH:7])=[O:5])=[C:9]([CH:29]([S:36][C:37]3[NH:41][N:40]=[N:39][N:38]=3)[CH2:30][CH2:31][S:32](=[O:34])(=[O:35])[NH2:33])[CH2:10][S:11][C@H:12]12)=[O:27])(=[O:21])=[O:20]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 1784507027-(2,2,2-Trifluoroethylsulfonylacetamido)-3-[1-(2-sulfamoylethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acid t-butyl ester

Product 1

HCID 178514771HCID 178514771, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The ester is dissolved in acetonitrile and trifluoroacetic acid is added. The solution is stirred for three hours, then evaporated to dryness to give the title compound.

Workup

  1. customevaporated to dryness

Sources & evidence

ORD record
ord-538e9142dced45789ccc3bd761e92700
Source dataset
uspto-grants-1979_02
Patent number
US04139701

Reaction notes

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