HuagongsheHuagongshe Chemistry Print Report · For research reference only
19-t-Butyldimethylsiloxy-4-androstene-3,17-dione → 19-t-Butyldimethylsiloxy-6alpha-methyl-4-androstene-3,17-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 19-t-Butyldimethylsiloxy-4-androstene-3,17-dione | HCID 10573974 | — |
| Reactant | 19-Hydroxy-6alpha-methyl-4-androstene-3,17-dione | HCID 70583925 | — |
| Product | 19-t-Butyldimethylsiloxy-6alpha-methyl-4-androstene-3,17-dione | HCID 22803259 | — |
| Product | 3-t-Butyldimethylsiloxy-19-hydroxy-5-androsten-17-one acetate | HCID 131711428 | — |
Reaction Steps
Following essentially the same procedure and substituting 19-hydroxy-6α-methyl-4-androstene-3,17-dione and 3β,19-dihydroxy-5-androsten-17-one 19-acetate for the 19-hydroxy-4-androstene-3,17-dione above results in the preparation of 19-t-butyldimethylsiloxy-6α-methyl-4-androstene-3,17-dione and 3-t-butyldimethylsiloxy-19-hydroxy-5-androsten-17-one acetate, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04139617 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-7cd645e76005409d8f763e6cfa22a618 |
| Source note | uspto-grants-1979_02 |