Water → 3beta,17beta-Di(triphenylsiloxy)-5-androsten-19-ol

Participants

Reaction Steps

To an ether solution of 3β,17β-di(triphenylsiloxy)androst-5-en-19-ol acetate is added a suspension of lithium aluminum hydride in ether. After refluxing for a period of one hour, water is cautiously added, the ether solution is separated, dried over sodium sulfate and evaporated under reduced pressure. The residue when purified from an acetone-hexane mixture results in the preparation of the desired 3β,17β-di(triphenylsiloxy)-androst-5-en-19-ol.

Provenance & Evidence