3beta,17beta-Di(triphenylsiloxy)-5-androsten-19-ol → 3beta,17beta-Di(triphenylsiloxy)-5-androsten-19-one

Participants

Reaction Steps

Substituting 17β,19-dihydroxy-1α,17α-dimethyl-5-androsten-3-one, 19-hydroxy-1α-methyl-5-androstene-3,17-dione, 17β,19-dihydroxy-4α,6,17α-trimethyl-5-androsten-3-one, 17β-(2'-tetrahydropyranyloxy)-5-androsten-19-ol and 3β,17β-di(triphenylsiloxy)-5-androsten-19-ol for the 17α-methyl-5-androstene-3β,17β,19-triol 3,17-diacetate above results in the preparation of 17β-hydroxy-1α,17α-dimethyl-5-androstene-3,19-dione, 1α-methyl-5-androstene-3,17,19-trione, 17β-hydroxy-4α,6,17α-trimethyl-5-androstene-3,19-dione, 17β-(2'-tetrahydropyranyloxy)-5-androsten-19-one and 3β,17β-di(triphenylsiloxy)-5-androsten-19-one, respectively.

Provenance & Evidence