Hydrochloric Acid → HCID 21670873, compound

HRID 1390857Notes

Reaction equation

HRID 1390857 reaction equation
[Cl:1]Cl.[CH3:3][O:4][C:5]1([O:13][CH3:14])[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[N:11][OH:12].Cl>C(Cl)Cl>[Cl:1][CH:10]1[CH2:9][CH2:8][CH2:7][C:6](=[N:11][OH:12])[C:5]1([O:4][CH3:3])[O:13][CH3:14]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 24526ChlorineHCID 71365596N-(2,2-Dimethoxycyclohexylidene)hydroxylamine

Product 1

HCID 21670873HCID 21670873, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following the general procedure of Example 1, about 7.5 parts of elemental chlorine were added over a 21/2 hour period to a solution of 17.3 parts of 2,2-dimethoxycyclohexanone oxime and a catalytic amount of anhydrous hydrogen chloride dissolved in about 85 parts dry methylene chloride. The reaction contents were maintained at a temperature of about 25° to 35° C. under a dry nitrogen atmosphere. After the addition was completed, the contents were allowed to stir for an additional half hour and were then treated by the procedure as described in Example 1. There was obtained 19.9 parts (90% of theory) of product 3-chloro-2,2-dimethoxycyclohexanone oxime as determined by nuclear magnetic resonance spectroscopy.

Workup

  1. customThe reaction contents
  2. temperaturewere maintained at a temperature of about 25° to 35° C. under a dry nitrogen atmosphere
  3. additionAfter the addition
  4. additionwere then treated by the procedure

Sources & evidence

ORD record
ord-32ef101c8ff54a36bf65774ed4bd4ff1
Source dataset
uspto-grants-1979_02
Patent number
US04140717

Reaction notes

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