Hydrochloric Acid → HCID 73177919, compound

Participants

Reaction Steps

Following the general procedure of Example 1, to a solution of 4.73 parts of 4,4-dimethoxy-3-oximinoheptane and 0.2 parts anhydrous hydrogen chloride dissolved in 20 parts dry methylene chloride, at 30 to 35° C., under a dry nitrogen atmosphere, was added 1.8 parts of elemental chlorine over a 1/2-hour period. After the addition, the contents were stirred for 1/2-hour and then treated according to the procedure in Example 1 to yield 3.5 parts of 5-chloro-4,4-dimethoxy-3-oximinoheptane as determined by nuclear magnetic resonance spectroscopy.

Provenance & Evidence