1-Chloro-2,4-difluoro-5-nitrobenzene → 2,4-Difluoroaniline
Reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[C:5](Cl)=[CH:4][C:3]=1[N+:10]([O-])=O.[H][H]>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[NH2:10]Participants
3
Procedure
hydrogenating the 2,4-difluoro-5-chloronitrobenzene with hydrogen in the presence of a hydrogenation catalyst to form 2,4-difluoroaniline.
Sources & evidence
- ORD record
- ord-eb18b98d0ac148f6835c6826267f584c
- Source dataset
- uspto-grants-1979_02
- Patent number
- US04140719
Reaction notes
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